Ulva lactuca a natural occurring source of minerals to promote bone health and sustain athlete performance

From Top Italian Scientists Journal
Published
September 5, 2024
Title
Ulva lactuca a natural occurring source of minerals to promote bone health and sustain athlete performance
Authors
Giovanni Ficarra, Rita Lauro, Laura De Maria, Natasha Irrera, Nicola Cicero, Alessandra Bitto.
DOI
10.62684/TPMV8987
Keywords
Ulva lactuca; bone health; BMP-6, RUNX-2, Osteocalcin.
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Giovanni Ficarra(1), Rita Lauro(2), Laura De Maria(1), Natasha Irrera(2), Nicola Cicero(1), Alessandra Bitto(2)

(1) Department of Biomedical Sciences, Dental Sciences, and Morpho-Functional Imaging, University Hospital, Messina, Italy.

(2) Department of Clinical and Experimental Medicine, University Hospital, Messina, Italy.

Correspondence to: Alessandra Bitto, MD, PhD, Department of Clinical and Experimental Medicine, University of Messina, Torre Biologica 5th floor, “AOU” Policlinico G. Martino. Via C. Valeria, Gazzi, 98125 Messina, Italy, E-mail: abitto@unime.it

Abstract

The purpose of this study was to identify if the components extracted from Ulva lactuca might have some positive effect in maintaining and improve osteoblast function. The fresh Ulva was lyophilized, and the extract was characterized before testing. The osteoblasts were cultured in standard conditions and the lyophilized extract was tested at 1mg/ml for up to 48 hrs. s markers of osteoblast function and proliferation BMP-6, RUNX-2 and Osteocalcin were analyzed on the mRNA extracted from the osteoblast. The results showed a significant increase, especially after 48 hrs in the production of osteocalcin mRNA which suggest a role for this extract in maintaining bone health. Although preliminary these data indicate that the extract from Ulva can be used as supplements for human use especially in those conditions where minerals and antioxidants are more needed.

Declarations

Conflict of Interest

AB and NI are co-funders of SunNutraPharma srl a spin-off company of the University of Messina

Funding

This research has been performed using fundings from SunNutraPharma srl

Author Contributions

GF and AB conceived and wrote the paper RL and LDM produced data NI and NC revised and analyzed data

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