Optical Coherence Tomography Angiography in Glaucoma: a review on structural-functional relationship

From Top Italian Scientists Journal
Published
September 5, 2024
Title
Optical Coherence Tomography Angiography in Glaucoma: a review on structural-functional relationship
Author
Luciano Quaranta
DOI
10.62684/BFIT3273
Keywords
Optical Coherence Tomography Angiography; OCTA; Glaucoma.
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Luciano Quaranta

Centro Oculistico Italiano, Brescia, Italy

Abstract

Optical coherence tomography angiography (OCTA) is a non-invasive imaging tool for visualizing the ophthalmic microvasculature. Vessel density (VD) is mainly used as a metric for quantifying the ophthalmic microvasculature. The anatomic area of interest for OCTA in glaucoma are the optic nerve head area including the peripapillary region, and the macular region. Specifically, VD of the superficial peripapillary and superficial macular microvasculature is reduced in glaucoma patients compared to normal subjects. Recently VD has been correlated with functional deficits as measured by visual field (VF). The clinical applicability of OCTA in glaucoma management is limited due to the prevalence of imaging artifacts, and the knowledge of primary or secondary impairment of blood flow and VD in glaucoma. Overall, OCTA can play a complementary role in structural OCT imaging and VF testing to aid in the monitoring of glaucoma.

Declarations

Conflict of Interest

The Author declares that there is no conflict of interest.

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