View source for Ulva lactuca a natural occurring source of minerals to promote bone health and sustain athlete performance

{{DISPLAYTITLE:Ulva lactuca a natural occurring source of minerals to promote bone health and sustain athlete performance}}{{#seo:
|title=Ulva lactuca a natural occurring source of minerals to promote bone health and sustain athlete performance - Top Italian Scientists Journal
|description=The purpose of this study was to identify if the components extracted from Ulva lactuca might have some positive effect in maintaining and improve osteoblast function.
|keywords=Ulva lactuca; bone health; BMP-6, RUNX-2, Osteocalcin.
|citation_author=Ficarra,Giovanni; Lauro,Rita; De Maria,Laura; Irrera, Natasha; Cicero,Nicola; Bitto,Alessandra  
|citation_journal_title=Top Italian Scientists Journal 
|citation_publication_date=2024/06/05 
|citation_title=Ulva lactuca a natural occurring source of minerals to promote bone health and sustain athlete performance
|citation_keywords=Ulva lactuca; bone health; BMP-6, RUNX-2, Osteocalcin.
|citation_publisher=Top Italian Scientists
|citation_volume=1
|citation_issue=4
|citation_doi=10.62684/TPMV8987
|citation_issn=3033-5132
|}}{| class="wikitable" style="float:right ;border:solid 1px #a2a9b1; background-color: #f8f9fa" cellpadding="5"
|+ <span style="font-size:18px;"></span>
|- 
| '''Published'''
|-
| September 5, 2024
|-
| '''Title''' 
|-
| style="width:200px;" | Ulva lactuca a natural occurring source of minerals to promote bone health and sustain athlete performance
|- 
| '''Authors'''
|-
|   Giovanni Ficarra, Rita Lauro, Laura De Maria, Natasha Irrera, Nicola Cicero, Alessandra Bitto.
|-
| '''DOI'''
|-
| [https://doi.org/10.62684/TPMV8987 10.62684/TPMV8987]
|-
| '''Keywords'''
|-
| Ulva lactuca; bone health; BMP-6, RUNX-2, Osteocalcin.
|-
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|}
'''Giovanni Ficarra'''<sup>(1)</sup>, '''Rita Lauro'''<sup>(2)</sup>, '''Laura De Maria'''<sup>(1)</sup>, '''Natasha Irrera'''<sup>(2)</sup>, '''Nicola Cicero'''<sup>(1)</sup>, '''[https://www.topitalianscientists.org/tis/23926/Alessandra_Bitto_-_Top_Italian_Scientist_in_Biomedical_Sciences Alessandra Bitto]'''<sup>(2)</sup>

<sup>(1)</sup> Department of Biomedical Sciences, Dental Sciences, and Morpho-Functional Imaging, University Hospital, Messina, Italy.

<sup>(2)</sup> Department of Clinical and Experimental Medicine, University Hospital, Messina, Italy.

''Correspondence to'': Alessandra Bitto, MD, PhD, Department of Clinical and Experimental Medicine, University of Messina, Torre Biologica 5th floor, “AOU” Policlinico G. Martino. Via C. Valeria, Gazzi, 98125 Messina, Italy, E-mail: abitto@unime.it

==Abstract==
The purpose of this study was to identify if the components extracted from Ulva lactuca might have some positive effect in maintaining and improve osteoblast function. The fresh Ulva was lyophilized, and the extract was characterized before testing. The osteoblasts were cultured in standard conditions and the lyophilized extract was tested at 1mg/ml for up to 48 hrs. s markers of osteoblast function and proliferation BMP-6, RUNX-2 and Osteocalcin were analyzed on the mRNA extracted from the osteoblast. The results showed a significant increase, especially after 48 hrs in the production of osteocalcin mRNA which suggest a role for this extract in maintaining bone health. Although preliminary these data indicate that the extract from Ulva can be used as supplements for human use especially in those conditions where minerals and antioxidants are more needed.

==Declarations==

===Conflict of Interest===
AB and NI are co-funders of SunNutraPharma srl a spin-off company of the University of Messina

===Funding===
This research has been performed using fundings from SunNutraPharma srl

===Author Contributions===
GF and AB conceived and wrote the paper
RL and LDM produced data
NI and NC revised and analyzed data

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[[Category:Open Access]]

[[Category:Article]]

[[Category:Biomedical Sciences]]