View source for Leadless pacemaker retrieval from the left pulmonary artery in a patient with left persistent vena cava a case report

{{DISPLAYTITLE:Leadless pacemaker retrieval from the left pulmonary artery in a patient with left persistent vena cava: a case report}}{{#seo:
|title=Leadless pacemaker retrieval from the left pulmonary artery in a patient with left persistent vena cava: a case report - Top Italian Scientists Journal
|description=Leadless pacemakers (LPMs) represent an important advancement in cardiac pacing, particularly for patients with venous access limitations or a history of device-related complications.
|keywords=Leadless pacemaker; Device dislodgement; Pulmonary artery retrieval; Persistent left superior vena cava; Percutaneous extraction.
|citation_author=Sirignano,Anna;Di Rosa,Rita;Petrassi,Marco;Albanesi,Roberta;Biondi-Zoccai,Giuseppe;Versaci,Francesco
|citation_journal_title=Top Italian Scientists Journal 
|citation_publication_date=2025/09/01 
|citation_title=Leadless pacemaker retrieval from the left pulmonary artery in a patient with left persistent vena cava: a case report
|citation_keywords=Leadless pacemaker; Device dislodgement; Pulmonary artery retrieval; Persistent left superior vena cava; Percutaneous extraction.
|citation_publisher=Top Italian Scientists
|citation_volume=2
|citation_issue=4
|citation_doi=10.62684/UAZG9928
|citation_issn=3033-5132
|}}
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| '''Published'''
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| September 1, 2025
|-
| '''Title''' 
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| style="width:200px;" | Leadless pacemaker retrieval from the left pulmonary artery in a patient with left persistent vena cava: a case report
|- 
| '''Authors'''
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|   Anna Sirignano, Rita Di Rosa, Marco Petrassi, Roberta Albanesi, Giuseppe Biondi-Zoccai, Francesco Versaci.
|-
| '''Keywords'''
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|   Leadless pacemaker; Device dislodgement; Pulmonary artery retrieval; Persistent left superior vena cava; Percutaneous extraction.
|-
| '''DOI'''
|-
| [https://doi.org/10.62684/UAZG9928 10.62684/UAZG9928]
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| '''Downloads'''
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|  style="text-align: center;" | [[File:PDF_file_icon.png|center|50px|'''Download PDF'''|link=https://journal.topitalianscientists.org/images/b/bd/Leadless_pacemaker_retrieval_from_the_left_pulmonary_artery_in_a_patient_with_left_persistent_vena_cava_a_case_report.pdf]]
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Anna Sirignano <sup>(a)</sup>, Rita Di Rosa <sup>(a)</sup>, Marco Petrassi <sup>(a)</sup>, Roberta Albanesi <sup>(a)</sup>, '''[https://www.topitalianscientists.org/tis/2587/Giuseppe_Biondi_Zoccai_-_Top_Italian_Scientist_in_Biomedical_Sciences Giuseppe Biondi-Zoccai]''' <sup>(b,c)</sup>, Francesco Versaci <sup>(a)</sup>.

<sup>(a)</sup> Division of Cardiology, Santa Maria Goretti Hospital, Latina, Italy

<sup>(b)</sup> Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy

<sup>(c)</sup> Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy



''Correspondence to'':  Dr. Anna Sirignano, Division of Cardiology, Santa Maria Goretti Hospital, Via Lucia Scaravelli, 04100 Latina, Italy. Email: an.sirignano@gmail.com


==Abstract==
Leadless pacemakers (LPMs) represent an important advancement in cardiac pacing, particularly for patients with venous access limitations or a history of device-related complications. Although implantation techniques are standardized, percutaneous retrieval of LPMs remains a challenging and rarely performed procedure. We present the case of an 85-year-old male with persistent left superior vena cava (PLSVC) and multiple prior pacemaker interventions, who presented with leadless pacemaker dislodgement into a peripheral branch of the left pulmonary artery. The device was successfully retrieved percutaneously using a transfemoral approach involving two different-sized snares and a deflectable catheter system, overcoming significant technical challenges and secondary migration into the dilated coronary sinus. This case underscores the considerable procedural issues of LPM retrieval in complex anatomical settings and highlights the importance of tailored interventional strategies to ensure safe device extraction.

==Declarations==
=== Acknowledgements ===
This manuscript was drafted with the assistance of artificial intelligence tools, such as ChatGPT 4 (OpenAI, San Francisco, CA, USA), Mage (Mage, New York, NY, USA), in keeping with established best practices (Biondi-Zoccai G, editor. ChatGPT for Medical Research. Torino: Edizioni Minerva Medica; 2024). The final content, including all conclusions and opinions, has been thoroughly revised, edited, and approved by the authors. The authors take full responsibility for the integrity and accuracy of the work and retain full credit for all intellectual contributions. Compliance with ethical standards and guidelines for the use of artificial intelligence in research has been ensured.

=== Conflict of Interest ===
The Authors declare that there is no conflict of interest.

===Disclosure===
Giuseppe Biondi-Zoccai has consulted, lectured and/or served as advisory board member for Abiomed, Advanced Nanotherapies, Aleph, Amarin, AstraZeneca, Balmed, Cardionovum, Cepton, Crannmedical, Endocore Lab, Eukon, Guidotti, Innovheart, Meditrial, Menarini, Microport, Opsens Medical, Synthesa, Terumo, and Translumina, outside the present work. All other authors report no conflict of interest.

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[[Category:Open Access]]

[[Category:Case Report]]

[[Category:Biomedical Sciences]]